Title Carpal tunnel syndrome: ethiopathogenesis, clinical manifestations, diagnostics, options of treatment, results, complications – literature review /
Translation of Title Carpal Tunnel Syndrome: Ethiopathogenesis, Clinical Manifestations, Diagnostics, Options of Treatment, Results, Complications – Literature Review.
Authors Malek, Nima
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Pages 29
Keywords [eng] carpal tunnel syndrome, median nerve compression, nerve conduction studies, electromyography, corticosteroid injection for CTS, wrist splinting, ultrasound-guided injections, patient outcomes in CTS surgery, surgical vs conservative CTS management, open carpal tunnel release, endoscopic carpal tunnel release
Abstract [eng] Background: Carpal tunnel syndrome (CTS) is regarded as the most common entrapment neuropathy caused by compression of the median nerve within the carpal tunnel. This thesis aims to review carpal tunnel syndrome's pathophysiology, diagnosis, conservative treatments, and release surgery. Methods: To evaluate the pathophysiology, diagnosis, and treatment of carpal tunnel syndrome, I conducted a comprehensive literature search using PubMed and Google Scholar. I included articles published in English within the last 15 years, focusing on the most recent insights into carpal tunnel syndrome. Due to a notable gap in recent primary research, particularly addressing the pathophysiology of carpal tunnel syndrome, I extended my search to include older studies dating back to 2002. These older foundational works have provided a substantial understanding of the nerve compression mechanisms, microcirculatory changes, and the role of inflammatory mediators in carpal tunnel syndrome, which remain relevant to current clinical practices and research. The selection of studies was guided by a combination of keywords such as "Carpal Tunnel Syndrome", "pathophysiology", "diagnosis", "treatment", and "nerve compression" among others. Each article was evaluated for its relevance to the core topics of pathophysiology, diagnosis, and treatment of carpal tunnel syndrome. Methodological rigor was assessed by examining the study design, data collection methods, and analysis techniques. Conclusion: Carpal tunnel release surgery is the gold standard long-term treatment for carpal tunnel syndrome. While conservative treatments like glucocorticoid injections are useful initial options, especially for mild to moderate cases of carpal tunnel syndrome, their effects are mostly short-term. The pathophysiology of carpal tunnel syndrome is complex and involves multiple factors that lead to median nerve compression under the transverse carpal ligament. Diagnosis relies on clinical evaluations with additional electrodiagnostic or sonographic tests. Surgical techniques include endoscopic surgery alongside traditional open surgeries, but no single approach universally outperforms others across all patient categories. Both types maintain efficacy, yet they differ in their recovery outcomes and potential for complications.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language English
Publication date 2024