| Abstract [eng] |
Cancer and chronic kidney disease (CKD) are prevalent global health challenges, often intersecting in clinical practice and complicating patient management. In 2020, an estimated 19.3 million new cancer cases and 10.0 million cancer-related deaths were reported worldwide, with lung cancer being the leading cause of cancer mortality. CKD affects 13.4% of the global population, with hemodialysis as the predominant treatment for end-stage renal disease. This review highlights the interplay between cancer and kidney disease, exploring the multifactorial etiologies of renal complications in cancer patients, including tumor-related factors, chemotherapy, and targeted therapies. Acute kidney injury, occurring in up to 29% of cancer patients, significantly impacts treatment outcomes and survival rates. The review underscores the importance of early detection, personalized dosing strategies, and multidisciplinary collaboration to optimize renal care in this population. Shared decision-making involving patients, caregivers, and healthcare providers is essential for navigating the complexities of treatment discontinuation and palliative care in advanced stages. |
