| Title |
Microextraction and gas chromatographic determination of parabens / |
| Translation of Title |
Parabenų mikroekstrakcija ir dujų chromatografinis nustatymas. |
| Authors |
Prichodko, Aleksandra |
| Full Text |
|
| Pages |
41 |
| Keywords [eng] |
parabens ; gas chromatography ; single drop microextraction ; hollow fibre liquid phase microextraction ; dispersive liquid-liquid microextraction |
| Abstract [eng] |
Parabens are effective antibacterial and anti-fungal agents and are used extensively as preservatives in cosmetics, food and pharmaceutical products. Because of the presence of parabens in the environment and their negative effects on human health, there is an increasing interest in their trace analysis. Since the concentration of parabens in the environment are rather low and cosmetics present rather complex matrices for the analysis, it is necessary to apply a preconcentration or isolation step prior to the chromatographic analysis. The aim of this work was to develop liquid-phase microextraction methods – single drop microextraction, hollow fibre liquid phase microextraction and dispersive liquid-liquid microextraction – for parabens and to apply the methods for determination of parabens in water samples and cosmetic products. Extraction conditions for single drop microextraction, hollow fibre liquid phase microextraction and dispersive liquid-liquid microextraction were optimized and the quality parameters of the suggested methods were calculated. The influence of derivatization on the paraben extraction efficiency was evaluated. Prepared microextraction methods were applied for the determination of parabens in real samples. |
| Type |
Summaries of doctoral thesis |
| Language |
English |
| Publication date |
2012 |
