| Abstract [eng] |
The aim of this work was to investigate pregnant women‘s gestational diabetes mellitus (GDM) diagnostic indicators in Siauliai county hospital Obstetrics - Gynecology clinic; to collect the data about their risk factors and do the analysis. The tasks: 1) to investigate the concentration of glucose in blood serum in the beginning of pregnancy, to do oral glucose tolerance test (OGTT) the 24th -28th week of pregnancy; 2) to repeat OGTT after childbirth to confirm the final diagnosis; 3) to collect the data about pregnant women‘s GDM diagnostic indicators and evaluate them; 4) to investigate the concentration of glucose in capillary blood of a newborn; 5) to collect the data about the complications of newborns and evaluate them. The collected data was grouped into 3 groups: risk, GDM and control. In the work the biggest attention was given to diagnostic indicators and the analysis of risk factors. The concentration of glucose in serum and blood is identified by analyzer EBIO compactin enzyme way. The concentration of glucose was identified for every woman in the beginning of pregnancy and for women in risk and GDM groups was done OGTT the 24th -28th week of pregnancy. By a doctor neonatologist’s prescription the analysis of the concentration of glucose in capillary blood of a newborn was done. For women, who came to the laboratory after childbirth was repeated OGTT for the final diagnosis. Glucosuria in urine is identified in an automatic way, according to the principle: sample – tape covered in special reagents – reaction – color change. The principle of device work is reflexive photometric. The analysis of urine for glucosuria is done for every woman several times in the time of pregnancy. After the review of scientific literature, exploring GDM diagnostic indicators, gathering the data on pregnant women’s GDM risk factors and their analysis we could propose that risk for GDM in Siauliai county hospital Obstetrics - Gynecology clinic is the same as in Lithuania and Europe. In Europe GDM is identified 0.15 – 4 % for all pregnant women, in Lithuania – 1.5 % [4]. According to my collected data GDM was diagnosed 0.97 %. Pregnant women, who belong to GDM risk group, are of elder age, that‘s why the toleration of glucose is often in disorder. In the work we set plus correlation between the concentration of GTM glucose in blood after glucose loading and the age of ill GDM women (r = 0.9972, p = 0.048). The majority had enlarged body mass index, lots of relatives had diabetes mellitus, ill-affected obstetric anamnesis was more frequent, had larger newborns more often than women at the control. We set plus correlation between put on weight in pregnancy time and the weight of a newborn for pregnant women in risk group (r = 0.3371, p = 0.001). Women‘s from risk and GDM groups newborns more often have hypoxia, more often hypoglycaemia is identified comparing with the control group. The control group was characterized in the feature that women put on weight in pregnancy that‘s why more larger newborns were born (plus correlation r = 0.3371, p = 0,001 is got). We could propose that in the future all these women will enter GDM risk group. |
