| Abstract [eng] |
Aim of the study: to measure venous and capillary blood glucose concentrations, certain biochemical markers and body mass index in patients with type 2 diabetes mellitus, to analyse risk factors for diabetes and their interaction. Materials and methods: We investigated 31 patients with type 2 diabetes, who attend Aukstadvaris Primary Health Care centre. Concentration of blood glucose and glycolysated haemoglobin (HbA1c) values were determined using biochemical analysers, and body mass index was calculated. Results: There was no statistically significant difference in the mean venous and capillary blood glucose concentration. The mean value was 8.7 mmol/l in the venous plasma and 8.9 mmol/l in the capillary blood. Glucose concentration was slightly higher in the capillary blood. The mean concentration of total cholesterol was slightly higher than normal (recommended value – less than 5.2 mmol/l). Concentration of the LDL cholesterol did not exceed the recommended value of less than 3.4 mmol/l. The patients investigated were determined to be at low risk for developing atherosclerosis. Concentration of HDL cholesterol was higher than recommended (normal value for men ≥ 1.03 mmol/l, for women – ≥ 1.29 mmol/l). Half of investigated men and 40 % of investigated women were deemed to have an increased risk of atherosclerosis. The concentration of blood triglycerides was only slightly higher than recommended normal value (recommended value – less than 1.7 mmol/l). 32 % of study subjects were found to be at increased risk for metabolic syndrome and atherosclerosis. The concentration of urea was higher than recommended (recommended values 2.3 – 6.4 mmol/l), whereas concentration of creatinine did not exceed normal values in all but one study subjects (recommended values 53 – 115 μmol/l). Only one patient had a normal body mass index, while the rest were either overweight or had a certain degree of obesity. There was a statistically significant positive correlation between the concentration of venous blood glucose and glycolisated haemoglobin values, and between the venous blood glucose and concentrations of urea and creatinine. A very weak positive correlation was determined between the body mass index of study subjects and concentration of triglycerides, and between the certain lipid values and concentration of venous blood glucose (although results were not statistically significant). Conclusion: Analysis of the results indicates that there is no statistically significant difference in the concentration of venous and capillary blood glucose in patients with type 2 diabetes. We can therefore conclude that capillary blood glucose measurements may be used for screening, adjustment of treatment and follow-up of diabetic patients. |
