| Abstract [eng] |
SUMMARY “The evaluation of the risk factors of atherosclerosis in patients visiting a primary health care centre“ Lipid and lipoprotein analysis is one of the most important in diagnosing cardiovascular diseases. The aim of the work was to study and evaluate the risk factors of atherosclerosis in patients visiting Utena Primary Health Care Centre. Tasks: to determine and evaluate the indicators of lipid and lipoprotein circulation in blood serum, to evaluate the relation of lipidogram indicators with the patients’ body mass index, arterial blood pressure and the influence of smoking of patients visiting a primary health care centre on the pathogenesis of atherosclerosis. Material and methods of the study: we have studied one hundred 50-70 years old men visiting a primary health care centre. Their arterial blood pressure (ABP), height and body weight were measured, body mass index (BMI) was calculated and lipidogram was determined: concentrations of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triacylglycerides (TAG) in blood serum by automated analyzer applying ferment photometric method. Results: BMI of the studied persons was 27.27 ± 2.30 kg/m². Only 9% had normal systolic ABP and the rest 91% had the increased systolic ABP. 96% had normal diastolic ABP and 4% had it increased. 52% of all the studied persons were non-smokers and 48% were smokers. It was established that the concentration of HDL-C and TAG in blood serum of the studied persons was normal. The concentrations of other lipidogram indicators were higher than recommended. Statistically significant positive correlation between TC and LDL-C, TC and TAG, systolic and diastolic ABP was established. No significant statistical relations between lipidogram indicators and BMI were established. Positive correlation of average intensity was established between systolic and diastolic ABP and between TC and TAG, and negative correlation between HDL-C and TAG. Statistically significant positive relations among TC, LDL-C and systolic ABP were established. No statistically significant relations between lipidogram indicators and diastolic ABP were establsihed. Correlation of smoking with lipidogram indicators was weak. Conclusions: having evaluated the risk factors of atherosclerosis in patients visiting a primary health care centre we have established that all the studied persons were overweight, had the increased systolic arterial blood pressure and the increased concentrations of the total and low-density lipoprotein cholesterol in blood serum. The risk of atherosclerosis was also proved by statistically significant relations between the concentrations of the total cholesterol, low-density lipoprotein cholesterol and systolic blood pressure. We have not established any statistically significant relations between smoking and lipidogram indicators. |
