| Abstract [eng] |
In the first part of doctoral thesis chemical and phase composition, as well as morphology of naturally derived calcium compounds (from dairy, corals, sea-shells and bovine bones) used in food industry were analysed and characterized. In this research a novel approach towards dairy derived calcium by characterizing it as a possible source of CaPs for biomedical applications was proposed as well as a method of synthesis of CHAp powders using sea shells, namely Macoma balthica, via sol-gel route was developed. To the best of our knowledge, there is no study aimed at producing CHAp powders from raw materials derived of natural–biological sea shells using an environmentally friendly water-based sol-gel reaction. There are no scientific data suggesting of using dairy powder as a source of calcium hydroxyapatite for biomedical applications as well. Moreover, iron (Fe) substituted sea shell derived CHAp for the first time was synthesized and characterized in this study. Thus, the aim of this work was to emphasize the importance of calcium phosphates, in particular hydroxyapatite, in human nutrition as well as in bone graft applications. In the subsequent part of the study, characterized calcium compounds with natural origin were used for the synthesis of calcium hydroxyapatite. This research was undertaken in order to investigate the possibilities of transforming a widely available sea-shell as well as dairy powder resource into a viable human bone replacement biomaterial. |
