Title Impact of combined anaesthesia on cognitive functions of patients after cardiac surgery /
Authors Benetis, Rimantas ; Širvinskas, Edmundas ; Lenkutis, Tadas ; Bukauskienė, Rasa ; Petkevičius, Petras ; Kasputytė, Greta
DOI 10.1053/j.jvca.2017.02.095
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Is Part of Journal of cardiothoracic and vascular anesthesia : Special issue: EACTA 2017 Abstracts: [32nd Annual congress of the European Association of Cardiothoracic Anaesthesiologists "Comprehensive cardiovascular cardiothoracic care (C⁴)" : April 19-21 2017, Berlin, Germany].. Philadelphia, PA : W.B. Saunders ; Elsevier Inc. 2017, vol. 31, suppl. 1, p. S27-S28, no. PP19.. ISSN 1053-0770
Keywords [eng] Cardiac surgical procedures ; Postoperative complications ; Anesthesia, general ; Anesthesia, epidural ; Cognition
Abstract [eng] Background and Goal: The incidence of postoperative cognitive dysfunction (POCD) occurs in 30-65% of patients after cardiac surgery. The aim of our study was to investigate the impact of general anaesthesia with thoracic epidural anaesthesia on cognitive functions after cardiac anaesthesia with CPB. Methods: 80 patients were enrolled into two groups: general anaesthesia (GA, n ¼ 42) and general anaesthesia with thoracic epidural anaesthesia (TEA, n ¼ 38). Neurocognitive tests were accomplished 1 day before surgery and 7 days postoperatively: MMSE, Six – item cognitive impairment test, WAIS Digit symbol substitution test. Results: All preoperative (baseline) test results did not differ significantly among TEA and GA groups. 7th-day WAIS test results did not differ much comparing TEA (20,03; SD 5,97) and GA (17,14; SD 6,48) groups. Comparing preoperative and postoperative WAIS test results there was a relevant decline in GA (preoperatively: 19 (SD 7,11); postoperatively 17,14 (SD 5,97) group. WAIS score change was significantly higher in GA groups, compared to TEA. There was no significant difference in 7th-day MMSE test results comparing TEA (median 28, min 23, max 30) and GA (median 28, min 18, max 30) groups. Patients in TEA group demonstrated better Six-item test results than in GA group at the 7th day after surgery (p¼ 0,16). Less points demonstrate better cognitive function, more points - cognitive dysfunction: GA median 2 (min 0, max 16) vs TEA median 2 (min 0, max 16) before surgery and GA median 4 (min 0, max 18) vs TEA median 2 (min 0, max 18) after surgery. Conclusions: Combined anaesthesia is not associated with POCD, compared to general anaesthesia. Memory and processing speed capabilities decrease after general anaesthesia.
Published Philadelphia, PA : W.B. Saunders ; Elsevier Inc
Type Conference paper
Language English
Publication date 2017