| Abstract [eng] |
Background. Influenza is one of the most common upper respiratory tract infections, which is especially dangerous for pregnant women and newborns. Due to changes in the immune system, cardiovascular and respiratory systems, complications of influenza occur more often in pregnant women than in the general population and are associated with unfavorable pregnancy and childbirth outcomes: premature birth, spontaneous abortion, fetal death. It has been scientifically proven that flu vaccinations are safe during pregnancy and protect the future newborn even up to 6 months. after birth. In the case of severe influenza infection and the occurrence of complications, pregnant women should be prescribed antiviral drugs. Aim: to review the influenza virus effects on the outcome of pregnant women and fetus, to evaluate the safety and efficacy of antiviral treatment and to assess the benefit-risk of vaccination. Methods: Literature review based on PubMed, Medline, Web of Science scientific databases. A total of 100 articles were found, of which 80 articles were analyzed using the following inclusion criteria: publications in English over the last 15 years, keywords were used influenza, pregnancy, vaccine, antiviral therapy, consequences. Results: According to research, flu-related adverse effects are more common in pregnant women compared to the general population. The most effective way to protect the mother and fetus is vaccination. It has been proven that vaccinations do not cause fetal malformations and do not complicate the course of pregnancy. In case of comorbidities, it is recommended to prescribe antiviral treatment for a severe course of the disease. Conclusions: Pregnant women are at higher risk of complications from the virus infection. Antiviral treatment is safe and should be given immediately. Vaccination against influenza should be recommended in all pregnant women, because it is safe and effective and reduces morbidity and mortality in both women and fetal. |
