Title Testicular cancer in two brothers of a quadruplet: a case report and a review of literature /
Translation of Title Dviejų ketvertuko brolių sėklidžių vėžys: atvejo aprašymas ir literatūros apžvalga.
Authors Ulytė, Agnė ; Ulys, Albertas ; Sužiedėlis, Kęstutis ; Patašius, Aušvydas ; Smailytė, Giedrė
DOI 10.6001/actamedica.v24i1.3458
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Is Part of Acta medica Lituanica.. Vilnius : Lietuvos mokslų akademijos leidykla. 2017, Vol. 24, No. 1, p. 12-17.. ISSN 1392-0138. eISSN 2029-4174
Keywords [eng] testicular cancer ; quadruplet ; multiple birth ; risk factors
Abstract [eng] and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister). Case description. Both patients were diagnosed at 21 years of age and died within two years from the diagnosis despite treatment. The third symptomless brother did not have testicular pathology. We also review the risk factors associated with testicular cancer, and the proposed hypotheses how a multiple birth results in an increased risk. The most consistent risk factors for testicular cancer are cryptorchidism, prior history of testicular cancer, and a positive familial history. According to different studies, the risk of testicular cancer in twins is higher from 22% to 30%, compared to the general population. Conclusions. To our knowledge, we have presented the first case of testicular teratoblastoma in brothers of a quadruplet.
Published Vilnius : Lietuvos mokslų akademijos leidykla
Type Journal article
Language English
Publication date 2017
CC license CC license description