| Title |
Corrosion and biocompatibility studies of bioceramic alumina coatings on aluminum alloy 6082 / |
| Authors |
Matijošius, Tadas ; Bakutė, Neringa ; Padgurskas, Juozas ; Selskienė, Aušra ; Žarkov, Aleksej ; Grigucevičienė, Asta ; Kavaliauskaitė, Justina ; Stirkė, Arūnas ; Asadauskas, Svajus |
| DOI |
10.1021/acsami.5c00532 |
| Full Text |
|
| Is Part of |
ACS applied materials & interfaces.. Washington : American chemical society. 2025, vol. 17, iss. 17, p. 24901-24917.. ISSN 1944-8244. eISSN 1944-8252 |
| Keywords [eng] |
porous Al2O3 ; simulated body fluid ; cell adhesion ; viability ; osteosynthesis plates |
| Abstract [eng] |
Recent advances in ceramic materials, particularly porous alumina (Al2O3), have significantly enhanced the safety and efficacy of medical implants by improving biocompatibility and modulating cellular behavior for biomedical applications. Variations in the surface structure and chemical composition of porous Al2O3 promote different biological responses and coating stability, highlighting the need for further biological and corrosion research. Traditional methods for producing alumina ceramics from powder are expensive, time-consuming, and limited in their ability to produce complex shapes and large structures due to the brittleness of alumina. This study evaluates the biocompatibility of bioceramic-coated aluminum (Al) alloy 6082 as a lightweight and cost-effective alternative for bone osteosynthesis plates. Al2O3 coatings were achieved through anodization using phosphoric and sulfuric acids. The untreated and anodized alloys were analyzed for chemical stability and biocompatibility and compared with medical-grade titanium alloy. All specimens exhibited excellent biocompatibility, demonstrating high adhesion and viability of the fibroblast cell line. Corrosion resistance and metal ion release were assessed in simulated body fluid, with all specimens effectively suppressing the release of Fe and toxic Al ions. The untreated Al alloy exhibited a higher release of Mn ions than the coated specimens. Notably, the bioceramic coating obtained in sulfuric acid demonstrated three orders of magnitude higher corrosion resistance, indicating its potential suitability for biomedical applications. By addressing the limitations of traditional alumina ceramics, our approach enables the fabrication of products in diverse sizes and shapes, offering a practical solution for creating customized biomedical implants. |
| Published |
Washington : American chemical society |
| Type |
Journal article |
| Language |
English |
| Publication date |
2025 |
| CC license |
|
