| Title |
Web-based GTalign: bridging speed and accuracy in protein structure analysis |
| Authors |
Dapkūnas, Justas ; Margelevičius, Mindaugas |
| DOI |
10.1093/nar/gkaf398 |
| Full Text |
|
| Is Part of |
Nucleic acids research.. Oxford : Oxford University Press (OUP). 2025, vol. 53, iss. W1, p. W291-W296.. ISSN 0305-1048. eISSN 1362-4962 |
| Abstract [eng] |
Accurate protein structure alignment is essential for understanding structural and functional relationships. Here, we introduce GTalign-web, a web-based implementation of GTalign, a spatial index-driven protein structure alignment tool, designed for accessibility and high-performance structural searches. Benchmarked against the DALI and Foldseek servers, GTalign-web demonstrates superior accuracy while maintaining rapid search times. Its utility is further highlighted in annotating uncharacterized proteins through searches against UniRef30. GTalign-web provides a useful resource for protein structure analysis and functional annotation and is available at https://bioinformatics.lt/comer/gtalign. This website is free and open to all users, and there is no login requirement. |
| Published |
Oxford : Oxford University Press (OUP) |
| Type |
Journal article |
| Language |
English |
| Publication date |
2025 |
| CC license |
|
