| Abstract [eng] |
2. Abstract Background: Obesity is a global health issue with its prevalence continuously rising. Therefore, bariatric surgery is gaining attention and relevance as a therapeutic intervention. A relatively new procedure compared to the more established surgical techniques, such as sleeve gastrectomy or Roux – en – Y – Gastric Bypass, is called gastric plication. It is showing promising results in regard to sustained weight loss and remission of obesity – related comorbidities. However, most of the existing literature is focussing on short term results, which is why mid to long term results will be the point of interest in this literature review. Methods: Comprehensive online literature research was conducted on PubMed, Cochrane and google scholar for articles published from 2010 until 2024. Studies representing outcomes from gastric plication were included when reporting ≥ 3-year of gastric plication results. The studies had to include at least one relevant outcome – in terms of weight loss including either excess weight loss, total weight loss or excess body-mass-index loss, patient´s remission of obesity-related comorbidities and complications. Results: In total 7 Studies (4 retrospective, 2 prospective case series and 1 Cohort Study), involving 1405 patients in total who underwent gastric plication, were included in the final analysis. Among the patients 78.5% were women and 21.5 % men. The mean age of the patients at the time of surgery was 38 years. The mean preoperative BMI was 39,82 kg/m2. The duration of follow up varied from 1 to 12 years. Two studies reported 3-year results, two studies reported 5-year results, one study showed 6-year results, another study presented up to 7-year results and another study reported up to 12-year results. Mean EWL% after 1, 3 and 5 years was 60.1%, 52.53% and 54.58% while mean TWL% was 24.79%, 18.85% and 19.33%. Mean EBMIL% at those time rates was 60.77%, 51.05% and 57.23%. Mean remission rates across all the studies were 73.11% for type 2 Diabetes Mellitus, 78% for patients with dyslipidaemia, 64.43% in arterial hypertension, 21% in gastroesophageal reflux disease reporting it only from one article, 78.33% for fatty liver such as 100% remission rate in obstructive sleep apnoea and degenerative joint diseases. Conclusion: Gastric plication is showing promising results in terms of sustained weight loss and improvements in obesity-related comorbidities. Complication rates are comparable to other well-established bariatric surgery procedures such as sleeve gastrectomy. By reviewing the existing literature, it becomes evident that gastric plication is recognized as a noteworthy option. Nevertheless, this procedure still lacks qualitative literature and studies especially for long-term results (>5 years). There is limited number of articles available so conducting a well-rounded conclusion for this procedure seems challenging for now. Furthermore, there is substantial heterogeneity among the included studies making comparisons to more established bariatric techniques challenging. |
