| Abstract [eng] |
Aim This scoping review aims to explore and synthesize current understanding of the comorbidity between adult Attention-Deficit/Hyperactivity-Disorder and trauma-related disorders (posttraumatic stress disorder and acute stress reaction), with particular focus on their historical development, neurobiological underpinnings, and treatment strategies. Methods An extensive search was carried out across historical accounts, diagnostic‑classification papers, neuroimaging and genetic studies, and contemporary treatment guidelines. Searches were performed in the major biomedical and psychological databases: MEDLINE/PubMed, Embase, APA PsycNET, Cochrane Library and Google Scholar. Results The review indicates that the comorbidity of adult Attention-Deficit/Hyperactivity-Disorder and Post-traumatic stress disorder not only shares clinical features such as inattention, restlessness, and emotional volatility but also converge on similar fronto‑limbic circuitry disruptions, blurring diagnostic boundaries. These overlaps complicate therapy yet create opportunities for future integrated pharmacological and psychotherapeutic strategies that address both attentional and trauma‑driven symptoms in tandem. Conclusions Overall, this review highlights current research and the need for future research into diagnostic trends and a more precise diagnostic framework, neurobiological and genetic studies, and combined treatment methods of adult Attention-Deficit/Hyperactivity-Disorder and Post-traumatic stress disorder. Keywords ADHD; PTSD; comorbidity; adult. |
