| Abstract [eng] |
Aim of the work: To review the latest literature on hypertriglyceridemia–induced acute pancreatitis, the applied treatment strategies, and potential preventive measures, as well as to assess the disease’s impact on patients' health and quality of life. Objectives: 1) To describe the etiology, pathogenesis, clinical course, diagnostics, treatment strategies, and preventive measures of hypertriglyceridemia–induced acute pancreatitis; 2) To review the literature on the disease’s impact on patients' health and quality of life. Methodology: The literature review and analysis were conducted based on a search of the Medline (PubMed), UpToDate, Elsevier Clinical Key, and Google Scholar databases. No restrictions were applied regarding the publication period. The following English–language keywords were used: hypertriglyceridemia and acute pancreatitis, triglycerides and acute pancreatitis, metabolic syndrome and acute pancreatitis. A total of 60 English–language sources were selected, whose abstracts or main texts aligned with the objectives of this review. Results and Conclusions: Hypertriglyceridemia is one of the main causes of acute pancreatitis, leading to a more severe disease course, longer hospitalization, and an increased risk of complications. Despite the existence of various treatment methods, there are no clear and universal therapeutic guidelines for this condition. Non–pharmacological treatment, based on lifestyle modifications, requires consistent patient monitoring and an active multidisciplinary approach to ensure long–term triglyceride control. To achieve better treatment outcomes, it is essential to strengthen the provision of individualized recommendations, promote patient education, and ensure close collaboration among specialists. Ambulatory dyslipidemia management should be intensified to ensure systematic triglyceride monitoring after an acute pancreatitis episode and patient discharge from the hospital. Acute pancreatitis during pregnancy is a rare but dangerous condition, whose development may be associated with hormonal changes, insulin resistance, and lipid metabolism disturbances. Early lipid monitoring during pregnancy, especially in high–risk groups, is essential. |
