| Abstract [eng] |
Clinical virology has been steadily on the rise with the advent of next-generation sequencing, bringing new knowledge on the gut virome. The gut virome is part of the microbiome, which, along with bacteria, archaea, fungi, and protozoa, are a variety of microorganisms that maintain homeostasis of body and cell functions. Evidence of this diverse and abundant population of viruses in the gastrointestinal (GI) tract has confirmed the existence of commensal viruses, which comprise the gut virome. There is evidence supporting the association of chronic inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis with the disruption of the gut microbiota homeostasis, and the role of viruses particularly bacteriophages on these chronic illnesses and treating antibiotic-resistant diseases. In this literature review, the importance of viruses and their effect on gut health and disease is highlighted. The scientific information is coming but still there is huge need for new data regarding importance of commensal virus on human health. |
