Title Hyperprolactinemia and hypoprolactinemia: causes and management /
Translation of Title Hyperprolactinemia and Hypoprolactinemia: Causes and Management.
Authors Rostum, Naz
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Pages 45
Keywords [eng] Prolactin, hyperprolactinemia, hypoprolactinemia, reproductive health, prolactinoma, dopamine agonists, infertility, lactation, pituitary gland, hormone regulation.
Abstract [eng] Prolactin is also defined as a lactogenic hormone that is secreted by the anterior pituitary gland. It is crucial to note menstrual cycle can be affected by this hormone and spermatogenesis in males. In order for the reproductive system and fertility to be adequate, a normal range of prolactin is crucial. However, there are also effects of excess or lack of prolactin, hyperprolactinemia and hypoprolactinemia on the reproductive and fertility capabilities. Hyperprolactinemia can also be associated with a decrease in libido among people, including men. This condition is also related to prolactinomas which are prolactin secreting tumors. The treatment of this disease includes dopamine that are known to decrease prolactin levels and tumor sizes. Aside from hyperprolactinemia, other forms include low prolactin levels which are not as common for most people. In association with other complications it can result in hormone imbalance, therefore affecting an individual’s reproductive health. Other health issues extending from hormone-specific to genetic problems can cause lactation failure in women as well as menstrual irregularity. Due to this effect, these conditions can result in hormone imbalance that can negatively affect reproductive health and diagnostic procedures such as blood tests and imagine examinations are crucial. If not treated, these conditions can cause reproductive tract dysfunction and various health complications. Due to recent improvements in diagnostic and treatment approaches, there has been significant advancements in diagnosing prolactin related disorders. The ongoing research of the various roles of prolactin in the body are still being carried out to help with more effective treatment methods. Along with investigations of the physiological roles of prolactin and how its fluctuations relate to treatment options for hyper and hypoprolactinemia, this literature review emphasizes the importance of hormone regulation for reproductive health.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language English
Publication date 2025