Title Informedness of patients participating in clinical research. analysis of tools used to evaluate the understanding of clinical trials information /
Translation of Title Informedness of Patients Participating in Clinical Research. Analysis of Tools Used to Evaluate the Understanding of Clinical Trials Information.
Authors Thoppil, Elizabeth Victoria
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Pages 41
Keywords [eng] Clinical Trials, Reading Comprehension, Informed Consent, Research Ethics
Abstract [eng] Informed consent is an important part of human research. It is important participants fully understand what they are getting into before joining a trial. Additionally, they should also know what rights they are entitled to. In this thesis multimedia tools, artificial intelligence, leaflets and other paper aids were compared to see how well they inform patients on the topic of informed consent in clinical research. Analyzing and identifying the need to improve of traditional informed consent forms. Complications that can complicate informed consent. How clinical trial recruitment faces similar challenges that relate to informed consent forms. Multiple articles related to the topic of informed consent forms in human subjects were analyzed to see if the traditional informed consent form is lacking and if there are viable alternatives. Articles covered many regions but were all published in the English language. The artificial intelligence ChatGPT 4 was used solely to define its function. The results found that the use of artificial intelligence chatbots in improving informedness of patients understanding of clinical trials appears to be the most promising. AI search engines also helped streamline the recruitment process. Examining multimedia tools found them to be a promising second place. Leaflets and other paper aids proved to not differ significantly compared to the traditional informed consent forms. A lack of understanding of informed consent can hamper patient enrollment. Minors require special considerations depending on their age, but they should receive at least some method of providing informed consent. Research in emergency situations tended to operate under an ‘act now ask questions later’ environment as everything is too time sensitive to put proper informed consent into action.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language English
Publication date 2025