| Title |
Massive malignant transformation in a patient with hidradenitis suppurativa during anti-tumor necrosis factor treatment |
| Authors |
Rudzikaitė, Gabija ; Jokubaitė, Jorinta ; Markevičius, Dominykas ; Pamedys, Justinas ; Raudonis, Tadas |
| DOI |
10.1097/ASW.0000000000000303 |
| Full Text |
|
| Is Part of |
Advances in skin and wound care.. Philadelphia : Wolters Kluwer Health, Inc.. 2025, vol. 38, iss. 5, p. 278-279.. ISSN 1527-7941. eISSN 1538-8654 |
| Keywords [eng] |
adalimumab ; hidradenitis suppurativa ; malignancy ; squamous cell carcinoma |
| Abstract [eng] |
Hidradenitis suppurativa (HS) is a chronic skin condition that can lead to significant morbidity and, in some cases, transformation to squamous cell carcinoma (SCC). This report details the case of a 53-year-old man with a history of HS treatment with adalimumab and systemic antibiotics who developed well-differentiated SCC. For this malignant transformation, the patient required aggressive management, including radiation therapy, wide excision, and reconstructive surgery. Follow-up showed no disease progression. This case highlights the importance of early detection, routine screening, and a multidisciplinary approach in managing the risk of SCC in patients with HS. |
| Published |
Philadelphia : Wolters Kluwer Health, Inc |
| Type |
Journal article |
| Language |
English |
| Publication date |
2025 |
| CC license |
|
