| Abstract [eng] |
Synthesis and investigation of precisely constructed anionic molecular brushes of various topologies is of growing interest. Due to the specific geometry and ionizable groups, they possess unique physicochemical properties and can be applied in various fields of science, medicine or industry as drug nanocarriers, materials for tissue engineering, stimuli-responsive coatings, etc. These polymers mimicking natural brush polymers (e.g., biolubricants) respond to different external stimuli, such as pH, ionic strength, solvent and temperature. Thus, anionic molecular brushes are of interest from both practical and fundamental points of view. The synthesis of molecular brushes with desired architecture and well-defined molecular characteristics is not trivial and often requires combination of several methods or development of new synthesis strategies. In this work, anionic molecular brushes of various topologies with poly(meth)acrylate or polystyrene-based backbone and poly((meth)acrylic acid) side chains were synthesized by the methods of RAFT (Reversible Addition-Fragmentation Chain Transfer) polymerization and click chemistry. Different composition random, diblock and triblock copolymers, including coil-brush, coil-brush-coil and brush-coil-brush structures, were synthesized. The molecular characteristics of well-defined anionic molecular brushes were determined by FT-IR and NMR spectroscopies, and SEC. The thermal behavior, ionization and micellization/aggregation in water-based solution of these polymers and wetting properties of polymer films were investigated. |
