| Title |
Enzymatic epoxidation strategies for the stereoselective synthesis of chiral epoxides |
| Authors |
Petkevičius, Vytautas ; Mügge, Carolin ; Tischler, Dirk ; Meškys, Rolandas |
| DOI |
10.1016/j.xcrp.2025.102794 |
| Full Text |
|
| Is Part of |
Cell reports physical science.. Cambridge, MA : Cell Press. 2025, vol. 6, iss. 9, art. no. 102794, p. [1-14].. ISSN 2666-3864 |
| Abstract [eng] |
Epoxides, a class of organic compounds that feature a highly reactive three-membered oxygen-containing ring, have gathered significant attention due to their remarkable reactivity and versatility. The strained epoxide group, which can also occur naturally, renders the compound class central in many industrial processes. The beauty of nature is that it provides a manifold repertoire of enzymes allowing the formation of these epoxides with regio- and stereo-selective information as desired for certain applications, like in the food, aroma, and pharmaceutical industries. Herein, powerful biocatalytic approaches as well as recent developments are discussed to provide a perspective on potent enzymatic epoxidation as well as to direct research toward the unknown unknowns of these systems. |
| Published |
Cambridge, MA : Cell Press |
| Type |
Journal article |
| Language |
English |
| Publication date |
2025 |
| CC license |
|
