| Title |
Infuzoterapijos pasirinkimas: subalansuoti ar nesubalansuoti kristaloidai? |
| Translation of Title |
Choice of infusion therapy: balanced or unbalanced crystalloids? |
| Authors |
Karmazinaitė, Martyna ; Kuprys, Rapolas |
| DOI |
10.53453/ms.2025.5.3 |
| Full Text |
|
| Is Part of |
Medicinos mokslai = Journal of medical sciences.. Kėdainiai : VšĮ Lietuvos sveikatos mokslinių tyrimų centras. 2025, vol. 13, iss. 3, p. 32-39.. ISSN 2345-0592 |
| Keywords [eng] |
intravenous infusion ; sepsis ; kidney injury ; cardiogenic shock ; traumatic brain injury |
| Abstract [eng] |
Background: Intravenous fluid therapy is essential in patient care, especially in intensive care. Emerging evidence suggests balanced crystalloids (BC), with plasma-like composition, may be preferable to unbalanced solutions (0.9% NaCl). This study aims to identify specific patient groups for whom balanced or unbalanced crystalloid solutions should be preferentially used. Aim: To evaluate the clinical effects of balanced versus unbalanced crystalloids in different patient populations— those with kidney injury, cardiac conditions, sepsis, and traumatic brain injury. Methodology: A literature review was conducted using PubMed database, analyzing 17 studies published between 2018 and 2024. The review focused on studies comparing the effects of NaCl 0.9% and balanced crystalloids across different patient populations. Results: BC are associated with a reduced risk of kidney complications compared to 0.9% NaCl. In septic patients, BC are linked to lower mortality and improved clinical outcomes. In cardiogenic shock, they reduce the need for vasopressors and lower lactate levels. However, in patients with traumatic brain injury or severe hypoxia following cardiac arrest, BC may increase intracranial pressure. In such cases, hypertonic saline solutions may be more appropriate. Conclusions: Balanced crystalloids are preferred in kidney injury, sepsis, and cardiogenic shock, while unbalanced hypertonic solutions are more suitable after out of hospital cardiac arrest or brain injury. |
| Published |
Kėdainiai : VšĮ Lietuvos sveikatos mokslinių tyrimų centras |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2025 |
| CC license |
|
