| Abstract [eng] |
Analysis of Biochemical Markers of Atherosclerosis and Evaluation of the Effectiveness of the Prevention of Heart and Vascular Disease. Background. The process of atherosclerosis is chronic. Many risk factors influence the progression of this chronic inflammatory disease. We can reduce cardiovascular morbidity not only by early detection of people, who are at high risk of suffering, by effective use of prevention program funding, but also by providing effective treatment in a timely manner. The aim of this study was to evaluate the biochemical markers of atherosclerosis and the effectiveness of cardiovascular diseases prevention program in Vilnius City. Methods. Study participants were males and females between 18 to 83 years of age living in Vilnius City. A total of 474 residents of Vilnius City were investigated, of which 212 tests were conducted using a statefunded cardiovascular prevention program. In accordance to the instructions of a physician the following blood tests were performed: general cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, glucose and C-reactive protein. Results. The study showed that concentrations of TC, HDL-C and LDL-C are statistically significantly higher in the female group than in the male group. Mean while, the concentrations of triglycerides, glucose and CRP statistically did not differ significantly in the male and female groups. A statistically significant difference between TC, LDL-C, triglycerides and glucose was obtained from the evaluation of biochemical atherosclerosis markers in the different age groups. Lowest values were identified in the group of subjects under the age of 30, the highest, except for glucose, in the group of subjects aged 50-69. The same institution has been regularly carrying out research on 50% of the patients for over 5 years. Even with significant Lipidogram deviations, only 21.1% of men and 15.3% of women taking part in the prevention programs receive treatment. Conclusion. Lipidogram studies in patients,taking part in prevention programs,which show a high risk of cardiovascular diseases and ineffective prevention indicate that the issue of reducing the prevalence of these diseases will remain relevant for a long time to come. |
