| Abstract [eng] |
Aim. To assess the impact of hemophilia on the quality of life of people with hemophilia and to identify the factors influencing it. Objectives: 1. To analyse literature about the physical, social and psychological factors that influence the quality of life of people with hemophilia. 2. To assess the impact of prophylactic interventions described in the literature on the frequency of joint bleeding, joint condition and quality of life. 3. To compare the impact of hemophilia complications on quality of life in children and adults, based on age groups. Methods. The literature search was performed from October 2024 to March 2026 in PubMed, Google Scholar and Mendeley databases. After screening and quality assessment, 14 articles were selected for analysis. Results. Hemophilia is associated with a lower quality of life. Studies have shown that hemophilia involves physical, psychological and social factors. Progressive joint deterioration associated with hemophilic arthropathy leads to a decline in daily functioning and overall quality of life. Lower quality of life is also associated with bleeding into joints, pain, limitations in normal daily and physical activities, and increasing age. Regular prophylaxis impacts higher quality of life. Patients experience symptoms of depression and anxiety, as well as limitations in their social lives – the need to adapt the workplace and educational institution, also they experience difficulties in social relationships. Conclusions: 1. Quality of life is influenced by physical factors: joint haemorrhage, progressive joint damage, and pain. Limitations in daily activities and reduced functionality are also linked to social functioning. Social factors such as workplace and educational institution adaptation, unemployment, social relationships and support from family and specialists influence quality of life in hemophilia. Psychological factors are also important: the patient’s own perception of the disease, anxiety and emotional state: stress and depression. 2. Prophylactic interventions described in the literature are associated with less frequent joint bleeding, better joint condition, and a higher quality of life. 3. Age is associated with quality of life, which is rated higher among children than among adults. |
