Title Anti-reflux mucosal ablation (ARMA) as a novel minimally invasive treatment for severe gastroesophageal reflux disease in a child: the first pediatric case report
Authors Povilavičius, Jonas ; Tubutytė, Geistė ; Bagdonaitė, Kamilė ; Dulskas, Audrius ; Strumila, Arūnas ; Račytė, Austėja
DOI 10.3389/fped.2026.1812619
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Is Part of Frontiers in pediatrics.. Lausanne : Frontiers Media SA. 2026, vol. 14, p. 1-6.. eISSN 2296-2360
Keywords [eng] anti-reflux mucosal ablation ; endoscopic therapy ; gastroesophageal reflux disease ; neurological impairment ; pediatrics
Abstract [eng] Background – Antireflux mucosal ablation (ARMA) is a novel, minimally invasive endoscopic technique for the treatment of gastroesophageal reflux disease (GERD). Our case report evaluates the feasibility and early clinical outcomes of ARMA in a neurologically impaired pediatric patient with refractory GERD. Case description – A 9-year-old boy with spastic cerebral palsy presented with severe GERD refractory to a long-term proton pump inhibitor therapy. He suffered from profound oropharyngeal dysphagia and recurrent aspiration pneumonia requiring multiple hospitalization. An endoscopic ARMA procedure was performed under general anesthesia without intra-procedural complications or immediate adverse events. Early follow-up revealed improved reflux control, enhanced tolerance of gastrostomy feeding, and a reduced need for acid-suppressive therapy. No respiratory deterioration or procedure-related complications were observed. Conclusions – ARMA is a technically feasible, minimally invasive option for refractory GERD. While this initial case involved a high-risk, neurologically impaired child, the mechanism suggests broader applicability to other pediatric patients with medication-resistant GERD.
Published Lausanne : Frontiers Media SA
Type Journal article
Language English
Publication date 2026
CC license CC license description