Title Gimdinės kilmės nevaisingumo paplitimas ir etiologija
Translation of Title Uterine factor infertility prevalence and causes.
Authors Kolosovaitė, Karolina ; Sabonytė-Balšaitienė, Živilė
DOI 10.53453/ms.2026.6.10
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Is Part of Medicinos mokslai = Journal of medical science.. Kėdainiai : VšĮ Lietuvos sveikatos mokslinių tyrimų centras. 2026, vol. 14, iss. 4, p. 109-116.. eISSN 2345-0592
Keywords [eng] uterine factor infertility ; adenomyosis ; endometriosis ; etiology ; prevalence
Abstract [eng] Background. Infertility is a significant public health problem affecting approximately 15–17% of the reproductiveage population. Uterine factor infertility represents an important part of this condition and is associated with congenital and acquired uterine pathologies that impair embryo implantation and pregnancy maintenance. Aim. To describe the prevalence and etiology of uterine factor infertility based on recent scientific literature. Material and methods. A literature search was performed in the PubMed database following PRISMA guidelines. A total of 18 sources were included in the analysis according to predefined inclusion criteria: systematic reviews, literature reviews, clinical studies, and official documents addressing the prevalence and etiology of uterine factor infertility. Studies not meeting the topic, published in languages other than English, or lacking full-text access were excluded. Results. Infertility prevalence remains high both in Lithuania and worldwide; however, its true extent may be underestimated due to limited available data. Uterine factor infertility is caused by a heterogeneous group of congenital and acquired conditions, including Müllerian duct anomalies, adenomyosis, endometriosis, intrauterine adhesions, and uterine fibroids. These conditions impair embryo implantation and pregnancy maintenance through different mechanisms, reducing the success of natural and assisted reproduction. Conclusions. Uterine factor infertility is a complex group of conditions requiring an individualized and multidisciplinary approach for diagnosis and management.
Published Kėdainiai : VšĮ Lietuvos sveikatos mokslinių tyrimų centras
Type Journal article
Language Lithuanian
Publication date 2026
CC license CC license description