| Abstract [eng] |
Reaction of 4,6-dichloro-2-methylthiopyrimidine-5-carbaldehyde (1) with 3-substituted 4-amino-1,2,4-triazole-5-thiones (2a-g) at 50-60degreesC led to 7-chloro-9-methylthiopyrimido[5,4-f][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepines (3a-g) representing a new heterocyclic system. Performing of the reaction of I with 4-amino-1,2,4-triazole-5-thione (La) at room temperature gave 7-chloro-9-methylthio-5,6-dihydropyrimido[5,4-f][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepin-6-oI (5), which with equimolar amount of sodium methoxide afforded 7-methoxy-9-methylthiopyrimido[5,4-f][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine (6)... |
