| Title |
Kasos galvos vėžio ir lėtinio pankreatito diagnostikos keblumai / |
| Translation of Title |
Diagnostic difficulties in pancreas head cancer and chronic pancreatitis. |
| Authors |
Brimienė, Vilma ; Brimas, Gintautas ; Strupas, Kęstutis |
| DOI |
10.15388/LietChirur.2006.3.2261 |
| Full Text |
|
| Is Part of |
Lietuvos chirurgija.. Vilnius : Vilniaus universiteto leidykla. 2006, t. 4, Nr. 3, p. 177-191.. ISSN 1392-0995. eISSN 1648-9942 |
| Keywords [eng] |
chronic pancreatitis ; pancreatic carcinoma ; focal pancreatic lesions ; imaging of pancreas |
| Abstract [eng] |
Objective Differential diagnosis of focal pancreatic lesions often remains a dilemma in clinical practice. Our objective was to present the literature data of diagnostic accuracy in focal pancreatic lesions and the most effective algorithm in differential diagnosis of chronic pancreatitis and pancreatic cancer. Results There can be enough overlap in the features and imaging of the carcinoma of the head of the pancreas and chronic pancreatitis, and sometimes the differentiation is extremely difficult. This leads to either a major pancreatic resection for a benign disease in 5–10% of the patients or rejection of surgery for a potentially curable cancer. The diagnostic accuracy of the common methods (ultrasound, computer and magnetic resonance tomography, endoscopic sonoscopy, serologic markers) are limited; even combinations of preoperative tests and biopsy are not sensitive and specific in 100%. Conclusions There are no evidence-based data in the literature on an effective algorithm for the clinical approach to a patient who presents with this diagnostic dilemma in focal pancreatic lesions. As all attempts to arrive at a correct diagnosis should be pursued, a prospective randomised clinical trial to compare the accuracy of diagnostic methods and early diagnosis in pancreatic cancer was started at the Vilnius University Hospital "Santariškių klinikos". |
| Published |
Vilnius : Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2006 |
| CC license |
|
