| Title |
Kairiojo plaučio transplantacija žiurkei: eksperimentinio modelio paieškos / |
| Translation of Title |
Left lung transplantation in rat: search for the experimental model. |
| Authors |
Sipavičius, Remigijus ; Zorinas, Aleksejus ; Drobelytė, Dalia ; Šerpytis, Rokas ; Sirvydis, Vytautas-Jonas |
| DOI |
10.15388/LietChirur.2006.3.2263 |
| Full Text |
|
| Is Part of |
Lietuvos chirurgija.. Vilnius : Vilniaus universiteto leidykla. 2006, t. 4, Nr. 3, p. 195-199.. ISSN 1392-0995. eISSN 1648-9942 |
| Keywords [eng] |
lung transplantation ; experimental model ; donor ; rat |
| Abstract [eng] |
Objective To design a new or to adapt the existing experimental models of rat lung transplantation. Methods Both left lung autotransplantation and orthotopic transplantation are implemented in rat. At autotransplantation, the left lung is left in situ after pulmoplegia. After a settled ischaemic time the lung perfusion is restored. At transplantation, pulmoplegia is performed in the donor. Lungs are separated and preserved for a settled ischaemic time. The recipient‘s left lung is removed and the donor‘s left lung transplantation is performed. The graft‘s perfusion is restored. Results Eleven experiments were carried out, 5 of them successfully. The main reasons for failure were bronchial anastomosis dehiscence or bronchial tear and anesthetic overdosage. Conclusions Existing experimental models were successfully adapted in rat, capacitating the further lung transplantation research. |
| Published |
Vilnius : Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2006 |
| CC license |
|
