Title |
Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids / |
Authors |
Jakubkienė, Virginija ; Valiulis, Gabrielius Ernis ; Žvirblis, Mantas ; Žvinys, Gediminas ; Zubrienė, Asta ; Matulis, Daumantas |
DOI |
10.15388/CCT.2019 |
ISBN |
9786090701676 |
Full Text |
|
Is Part of |
Chemistry and chemical technology: Lithuanian chemists conference, 2019 May 16, Lithuanian Academy of Sciences, Vilnius: conference book.. Vilnius : Vilniaus universiteto leidykla, 2019. p. 63.. ISBN 9786090701676 |
Keywords [eng] |
pyrimidines ; hydroxamic acids ; HDAC8 inhibitory activity |
Abstract [eng] |
In continuation of our interest in the synthesis of biologically active heterocycles, a series of pyrimidine-based hydroxamic acids was prepared and evaluated as inhibitors of HDAC8. |
Published |
Vilnius : Vilniaus universiteto leidykla, 2019 |
Type |
Conference paper |
Language |
English |
Publication date |
2019 |