| Title |
Sepsio diagnostika / |
| Translation of Title |
Diagnosis of sepsis. |
| Authors |
Vosylius, Saulius |
| DOI |
10.15388/LietChirur.2008.4.2140 |
| Full Text |
|
| Is Part of |
Lietuvos chirurgija.. Vilnius : Vilniaus universiteto leidykla. 2008, t. 6, Nr. 4, p. 242-257.. ISSN 1392-0995. eISSN 1648-9942 |
| Keywords [eng] |
sepsis ; diagnosis ; infection ; systemic inflammatory response syndrome ; multiple organ failure ; inflammation mediators |
| Abstract [eng] |
Background / objective The diagnosis of sepsis has always been an object for discussion. Early diagnosis and therapy are important in the management of critically ill patients. Methods Diagnostic criteria for sepsis and related states are still not well defined. The International Intensive Care Society conference held in 1991 proposed and later in 2001 revised the definitions of sepsis and related conditions. Results Infection is a pathologic process caused by the invasion of normally sterile tissue or fluid or body cavity by pathogenic microorganisms. Sepsis is defined as systemic inflammation caused by infection. Clinical signs related to sepsis are not specific to infection. To diagnose and monitor sepsis and to guide therapy, currently it is necessary to employ a combination of parameters. The diagnosis of sepsis is supported by clinical criteria and confirmed by laboratory parameters and microbiological data. Severe sepsis are confirmed when sepsis is complicated by tissue hypoperfusion and organ dysfunction. Septic shock refers to a state of acute circulatory failure characterized by persistent arterial hypotension unexplained by other causes. Conclusions Early diagnosis of sepsis is crucial in providing adequate therapy and improving the outcome. The search for the parameters of the diagnosis and monitoring the progress of sepsis is continuing. It should be specific for the diagnosis of infection, reflect the systemic inflammation, and correlate well with inflammation intensity. |
| Published |
Vilnius : Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2008 |
| CC license |
|
