| Abstract [eng] |
The growth of allergic sensitization and allergic diseases in the society has been actively analyzed in the context of environmental factors. The “window of opportunity” for the prevention of allergic diseases lasts from the conception to the sixth’ month of life. The first vaccines fall into this period. Immunization, as a planned target effect on a particular response of the immune system during infancy and as an additional risk factor for the development of atopic dermatitis, allergic rhinitis and bronchial asthma, peaks the interest of scientists and public. Although during the recent years the focus on vaccination of allergic children has increased across the global scholarly literature, this problem still lacks sufficient attention in Lithuania. The aim of the study was to thoroughly analyze the links between vaccination and allergic diseases diagnosed under the real working conditions of a primary healthcare facility during the pre-school age, and to assess the safety of vaccinating children diagnosed with atopic dermatitis. In the retrospective “real-life” study of a primary health care practice, we determined, that allergic diseases are not more frequently diagnosed in completely vaccinated children in comparison to non-vaccinated or partially vaccinated children. The vaccination of children diagnosed with atopic dermatitis is safe, as there was no difference in the frequency of adverse reactions to the vaccines among children with atopic dermatitis and children with no allergic diseases diagnosed. Routine immunization in infancy is not associated independently with the frequency of diagnosing the allergic diseases, but antibiotic prescription in this period of life is a concerning factor related to the risk of allergic disease diagnosis in everyday primary healthcare practice. |
