| Title |
Generation of recombinant single-chain antibodies neutralizing the cytolytic activity of vaginolysin, the main virulence factor of Gardnerella vaginalis |
| Authors |
Plečkaitytė, Milda ; Mištinienė, Edita ; Lasickienė, Rita ; Žvirblis, Gintautas ; Žvirblienė, Aurelija |
| DOI |
10.1186/1472-6750-11-100 |
| Full Text |
|
| Is Part of |
BMC biotechnology.. London : BioMed Central Ltd. 2011, Vol. 11, Art. no. 100 [p. 1-9].. ISSN 1472-6750 |
| Abstract [eng] |
Generated scFvs is the first example of recombinant single-chain antibodies with VLY-neutralizing activity produced in prokaryote expression system. G. vaginalis caused infections continue to be a world-wide problem, therefore neutralizing recombinant antibodies may provide novel therapeutic agents useful in the treatment of bacterial vaginosis and other diseases caused by G. vaginalis. |
| Published |
London : BioMed Central Ltd |
| Type |
Journal article |
| Language |
English |
| Publication date |
2011 |
