Title Resuscitation following a bupivacaine injection for a cervical paravertebral block /
Authors Vosylius, Saulius ; Uvarovas, Valentinas ; Švedienė, Saulė ; Šatkauskas, Igoris
DOI 10.1515/med-2019-0112
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Is Part of Open medicine.. Warsaw : Sciendo, De Gruyter Poland. 2019, vol. 14, iss. 1, p. 953-958.. eISSN 2391-5463
Keywords [eng] Local anaesthetic ; Ventricular fibrillation ; Cardiopulmonary resuscitation ; Fat emulsions ; Intravenous
Abstract [eng] Background Cardiac arrest related to nerve blockade using a local anaesthetic is a rare event. We report a case of bupivacaine severe cardiovascular toxicity following cervical paravertebral nerve block. Case presentation A 44-year-old female was admitted to Republican Vilnius University Hospital, with symptoms of sustained severe pain in her neck that radiated to both arms. Multiple cervical intervertebral hernias with spinal stenosis were confirmed by magnetic resonance imaging. Following infiltration of the subcutaneous tissue with a 0.5 % bupivacaine solution, an 18-gauge spinal needle was used to perform the paravertebral block at the C6 level. Bupivacaine was injected in incremental doses to a total of 10 mL. Rapid loss of consciousness and cardiovascular collapse suggested a neuraxial injection of bupivacaine. Long-lasting cardiopulmonary resuscitation, including chest compressions, defibrillation attempts for refractory ventricular fibrillation, medications, mechanical ventilation, and intravenous lipid emulsion infusion, was successful. No severe adverse outcomes other than acute kidney injury and chest pain related to prolonged chest compressions were documented. Conclusions This case report emphasizes the necessity of ensuring adequate safety precautions to avoid local anaesthetic systemic toxicity. Lipid emulsion preparations should be available in all hospital settings where local anaesthetics are used for regional anaesthesia or pain management.
Published Warsaw : Sciendo, De Gruyter Poland
Type Journal article
Language English
Publication date 2019
CC license CC license description