| Abstract [eng] |
Introduction Meniere’s disease (MD) is is a disorder of the inner ear which causes episodes of vertigo.The exact pathogenesis of MD is still not clear, but histopathological studies demonstrate an indisputable link with the endolymphatic hydrops. Diagnostic criteria for the MD were revised in 2015 by the Barany Society. Pure tone audiometry (PTA) is the only objective, however, not specific diagnostic tool used based on criteria. Aim of the study We aimed to assess the significance of radiologic examination, peripheral vestibular system and balance testing when diagnosing Meniere’s disease. Objectives of the study 1. To assess the results of a complex (clinical and instrumental neuro-otology) evaluation of the peripheral vestibular system in different types of Meniere’s disease. 2. To evaluate changes in the endolymphatic system in 3T delayed contrast enhancement magnetic resonance images of the temporal bone in case of different types of Meniere’s disease. 3. To determine the prognostic value of instrumental and radiological examination of the peripheral vestibular system when diagnosing Meniere’s disease. 4. To propose a grading system of 3T delayed contrast enhancement magnetic resonance images of the temporal bone in case of Meniere’s disease. 5. To determine tests that are of higher value when diagnosing Meniere’s disease, thus should be performed when making the diagnosis. This prospective single-center cohort study was performed in Vilnius University Hospital, Santaros Clinics in 2015-2018. |
