| Title |
Ampermetrinio biojutiklio su alosterinio fermento sluoksniu kompiuterinis modeliavimas / |
| Another Title |
Modeling amperometric biosensors based on allosteric enzymes. |
| Authors |
Ričkus, Liutauras |
| Full Text |
|
| Is Part of |
Computational science and techniques.. Klaipėda : Klaipėdos universitetas. 2013, vol. 1, no 2, p. 205-213.. ISSN 2029-9966 |
| Keywords [eng] |
Biosensor ; Allosteric enzyme ; Mathematical modeling ; Hill coefficient |
| Abstract [eng] |
Computational modeling of a biosensor with allosteric enzyme layer was investigated in this study. The operation of the biosensor is modeled using non-stationary reaction-diffusion equations. The model involves three regions: the allosteric enzyme layer where the allosteric enzyme reactions as well as then mass transport by diffusion take place, the diffusion region where the mass transport by diffusion and non-enzymatic reactions take place and the convective region in which the analyte concentration is maintained constant. The biosensor response on dependency substrate concentration, cooperativity coefficient and the diffusion layer thickness on the same parameters have been studied. |
| Published |
Klaipėda : Klaipėdos universitetas |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2013 |
