Title Does coffee affect the duration of postoperative ileus following elective laparoscopic colectomy? A randomized prospective single-center study /
Another Title Kavos poveikis žarnyno veiklai po žarnyno laparoskopinės rezekcinės operacijos: perspektyvusis atsitiktinių imčių tyrimas.
Authors Dulskas, Audrius ; Klimovskij, Michail ; Vitkauskienė, Marija ; Samalavičius, Narimantas Evaldas
DOI 10.15388/LietChirur.2014.3084
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Is Part of Lietuvos chirurgija.. Vilnius : Vilniaus universiteto leidykla. 2014, t. 13, Nr. 2, p. 104-110.. ISSN 1392-0995. eISSN 1648-9942
Abstract [eng] Background / objective. Postoperative ileus is a common problem after colorectal surgery. A positive effect of coffee on the bowel motor activity has been described. It is still unclear whether coffee consumption decreases the risk of postoperative ileus. The aim of the study was to determine whether consuming an 8-ounce cup of coffee is effective in preventing or reducing postoperative ileus. Patients and methods From January 1st, 2013 to December 31st 2014, a prospective study is being performed at the Institute of Oncology of Vilnius University. Patients with a malignant or benign disease, undergoing elective laparoscopic colectomy, are assigned randomly before surgery to receive either coffee with caffeine (group 1), coffee without caffeine (group 2), or water (group 3) (100 ml three times daily) after the procedure. The primary endpoint is the time to first bowel movement, and the secondary endpoints are the time to the first flatus and the time to solid food tolerance. Results A total of 48 patients have been randomized, 16 to each group. Six patients were excluded: four due to a change in the surgical procedure, and two refused to participate. Patients’ demographic characteristics were similar in all groups. The time till the first bowel movement was significantly (p < 0.05) shorter in the decaffeinated coffee (3.23; SD 1.36) and coffee with caffeine (3.64; SD 1.29) groups versus the water group (3.90; SD 0.99). The time till the tolerance of solid food (1.63 and 2.42 versus 2.85; p < 0.05) and the time till the first flatus (1.44 and 1.66 versus 1.92; p < 0.05) showed a similar trend.
Published Vilnius : Vilniaus universiteto leidykla
Type Journal article
Language English
Publication date 2014
CC license CC license description