| Abstract [eng] |
The main focus of this dissertation is on the cobalt ferrite nanoparticles (NPs), their size, core and composition-dependent influence on antimicrobial efficiency. In this study, the CoFe2O4 NPs were synthesized by hydrothermal, co-precipitation, thermal decomposition and electrochemical methods. The structure, composition and surface morphology were subsequently characterized by TEM, SEM, EDX, Raman, FTIR, ICP-OES, XRD techniques. Their antimicrobial activity was tested against well-known typical pathogens, which usually cause skin, tissue, blood and respiratory infections. For the first time, the dependency of antimicrobial properties of cobalt ferrite NPs on their size, chemical composition and shell has been shown. Furthermore, the antimicrobial activity of silver and copper oxide-based coatings, and ultra-small gold NPs was described in more detailed. It was determined that thin porous anodic aluminium oxide films with encapsulated metallic Ag nanowires, as thin as ≤ 1.0 μm, provide the antimicrobial, decorative and anticorrosive properties for food packing alumina foil. It has been shown for the first time, that ultra-small gold and magnetite-gold hybrid NPs exhibit the potential antimicrobial properties against multidrug resistant bacteria such as S. enterica, S. aureus MRSA and A. baumannii. |
