| Title |
Hepatitis E genotype 3 virus isolate from wild boar is capable of replication in non-human primate and swine kidney cells and mouse neuroblastoma cells : |
| Authors |
Grigas, Juozas ; Simkute, Evelina ; Simanavicius, Martynas ; Pautienius, Arnoldas ; Streimikyte-Mockeliune, Zaneta ; Razukevicius, Dainius ; Stankevicius, Arūnas |
| DOI |
10.1186/s12917-020-02315-5 |
| Full Text |
|
| Is Part of |
BMC veterinary research.. London : BioMed Central. 2020, vol. 16, no. 1, art. no. 95, p. 1-11.. ISSN 1746-6148. eISSN 1746-6148 |
| Keywords [eng] |
Animal cell lines ; Hepatitis E virus ; Kidney cells ; Neuroblastoma cells ; Wild boar |
| Abstract [eng] |
BACKGROUND: Wild boar-derived hepatitis E (HEV) genotype 3 virus has been successfully isolated in cell lines of human origin only. Considering the zoonotic potential and possible extrahepatic localisation of genotype 3 strain, it is important to investigate the viability of cell lines of different animal and tissue origins. Therefore, the objective of the present study was to determine the permissiveness of non-human primate (MARC-145 and Vero) and swine (PK-15) cell lines of kidney origin, and a mouse neuroblastoma (Neuro-2a) cell line for isolation of wild boar-derived HEV genotype 3. [...]. |
| Published |
London : BioMed Central |
| Type |
Journal article |
| Language |
English |
| Publication date |
2020 |
| CC license |
|
