| Title |
Dauginis galvinių nervų pažeidimas, sergant Churgo-Strausso sindromu: klinikinis atvejis |
| Translation of Title |
Multiple cranial neuropathies in Churg-Strauss syndrome: case report. |
| Authors |
Rutkauskaitė, Gintautė ; Masaitienė, Raminta ; Dadonienė, Jolanta ; Jatužis, Dalius |
| DOI |
10.29014/ns.2019.14 |
| Full Text |
|
| Is Part of |
Neurologijos seminarai.. Vilnius : Rotas. 2019, t. 23, Nr. 2, p. 92-97.. ISSN 1392-3064. eISSN 2424-5917 |
| Keywords [eng] |
Churg-Strauss syndrome ; eosinophilic granulomatosis with polyangiitis ; ANCA-associated vasculitis ; multiple cranial neuropathies ; polyneuropathy. |
| Abstract [eng] |
Churg-Strauss syndrome (CSS), known as eosinophilic granulomatosis with polyangiitis, is a systemic small- to medium-sized vasculitis, characterized by chronic rhinosinusitis, asthma and eosinophilia. Churg and Strauss first described this syndrome in 1951. Histology of CSS usually discloses eosinophil-rich infiltrates, necrotising vasculitis, and eosinophilic-granulomatous inflammation. There are no clear pathophysiologic mechanisms that explain the development of CSS but association between CSS and HLA-DRB4 has been reported. Because of the frequent positivity of antineutrophil cytoplasmic antibodies (ANCAs), which are found in 30–40% of the cases, CSS has been grouped with ANCA-associated vasculitis. Nervous system manifestations are found in up to 70% of CSS patients, while cranial neuropathies are rarely diagnosed. Patients are treated with glucocorticoids and immunosuppressants. We describe a case report of a 68-year-old woman with a clinical diagnosis of Churg-Strauss syndrome and multiple cranial neuropathies. |
| Published |
Vilnius : Rotas |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2019 |
| CC license |
|
