| Abstract [eng] |
Background / objective Treatment of metastases in lung from other organs is serious clinic problem. There are controversies about the surgical treatment of metastases in lung. In this paper we have taken our data about the surgical treatment of metastases in lung from other organs. Methods of treatment of metastases in lung and the follow-up results are presented. Patients and methods In the Thoracic Clinic of Institute of Oncology Vilnius University in the course of 1998–2002 168 patient (pts) with metastases in lung from other tumors were treated surgically. There were 81 males and 87 females. Mean age of males was 59.5 years (range 23–83 years). Mean age of females was 55.1 years (range 23–77 years).The most common primary tumor in females was cancer of breast – 37 pts, from ovarian – 9, from uterus – 8, from renal cell – 8, from other lung – 5, from hepatobiliary – 3, from colon – 3, from rectal – 3, from sarcoma of soft tissue – 3, melanoma – 2, from nasopharynx, thyroid, stomach, osteosarcoma – 1. In males: renal cell – 17 cases, from other lung – 13, from colorectal – 9, from testis – 9, from larynx – 6, from thyroid – 5, from osteosarcoma – 5, from prostate – 5, from sarcoma of soft tissue – 3, stomach – 2, adrenal – 2, from bladder, melanoma, oral cavity – 1. Surgical treatment: in 5 cases – pneumonectomy, 31 – lobectomy , 40 – segmentectomy, 14 – wedge resection, 11 – metastasectomy, 26 – thoracotomy, 38 – videothoracoscopy with insufflation of talc. Results 40 pts died from the progression of disease, median survival – 7.5 month (range 1–27 month). The follow-up results were better after the radical operations: median survival of pts after lobectomy was 12.4 months, after segmentectomy – 10.2 months, after wedge resection – 10.5 months. In the cases of pleural dissemination the pts lived 3,4 months. Conclusions Surgical treatment of solitary metastases in lung is favourable for life prolongation of patients. The best follow-up results were received after surgical treatment of solitary metastases in lung in pts with colorectal and renal cell carcinoma. The follow-up results are unsatisfactory of pts with ovarian, breast carcinoma and melanoma. In many cases of this carcinoma was pleural dissemination with metastases. Insufflation of talc is recommended to patients with pleural effusion. |
