Title Has ROP antenatal risk factors? /
Another Title AR prieš gimimą yra NNR turi rizikos faktorių?
Authors Sirtautienė, Rasa ; Bagdonienė, Rasa ; Jurevičius, Bronius
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Is Part of Acta medica Lituanica. 2006, Vol. 13, no. 3, p. 207-211.. ISSN 1392-0138
Keywords [eng] Retinopathy of prematurity ; Histopathology
Abstract [eng] Background: Retinopathy of prematurity (ROP) is a disease affecting the formation of retinal blood vessels in the premature infant’s retina. Retinopathy of prematurity occurs when there is the cessation of normal retinal vascularization. Aim of the study – to review the development of the retina and its vasculature and to present unusual case of retinopathy of prematurity like changes found 26 hours after the birth of premature infant. Materials and methods: Fourteen eyes of the seven autopsied fetuses and infants born during 17–36 gestational weeks were investigated. Results: Histological pictures of the peripheral retina are presented. In 6 cases histology of the retina was similar as described in the literature and corresponded to normal retinal development. In one case (2 eyes) changes of retina were identified 26 hours after the premature birth. The findings correspond to the changes characteristic to the stage I ROP Conclusions: Understanding of the retinal development and angiogenesis is necessary to appreciate the earlier stages of the retinopathy of prematurity. We speculate that the development of ROP is determined not only by postnatal but also by certain antenatal factors.
Type Journal article
Language English
Publication date 2006