| Title |
Intracellular distribution of nontargeted quantum dots after natural uptake and microinjection / |
| Authors |
Damalakienė, Leona ; Karabanovas, Vitalijus ; Bagdonas, Saulius ; Valius, Mindaugas ; Rotomskis, Ričardas |
| DOI |
10.2147/IJN.S39658 |
| Full Text |
|
| Is Part of |
International journal of nanomedicine. 2013, Vol. 8, p. 555-568.. ISSN 1178-2013 |
| Keywords [eng] |
Carboxyl ; Endocytosis ; Green fluorescent protein ; Internalization ; Lysosome ; Multivesicular body-like structures ; Pathway ; Protein corona ; Ring-like vesicles ; Saturation |
| Abstract [eng] |
The sharp contrast of the intracellular distribution after microinjection of quantum dots in comparison with incubation as well as the limited transfer of quantum dots from vesicles into the cytosol and vice versa support the endocytotic origin of the natural uptake of quantum dots. Quantum dots with proteins adsorbed from the culture medium had a different fate in the final stage of accumulation from that of the protein-free quantum dots, implying different internalization pathways. |
| Type |
Journal article |
| Language |
English |
| Publication date |
2013 |
