| Title |
Acrylate-gelatin–carbonated hydroxyapatite(cHAP) composites for dental bone-tissue applications / |
| Authors |
Golubevas, Ričardas ; Stankevičiūtė, Živilė ; Žarkov, Aleksej ; Golubevas, Raimundas ; Hansson, Lars ; Raudonis, Rimantas ; Kareiva, Aivaras ; Garškaitė, Edita |
| DOI |
10.1039/D0MA00498G |
| Full Text |
|
| Is Part of |
Materials advances.. London : The Royal Society of Chemistry. 2020, vol. 1, no. 6, p. 1675-1684.. eISSN 2633-5409 |
| Keywords [eng] |
carbonated hydroxyapatite ; composites, dental bone-tissue ; scaffolds |
| Abstract [eng] |
In this study, multi-composite scaffolds composed of dipentaerythritol hexa-acrylate (DPHA), ethylene glycol dimethacrylate (EGDMA), gelatin, and carbonated hydroxyapatite (cHAP) have been made. Percentage ratio of polymer matrix to gelatin was varied 50/50, 75/25, and 95/5 to change the porosity of the resultant scaffolds. The structure, crystallinity, and phase composition of the cHAP were confirmed by FTIR, Raman, XRD and Rietveld analyses, TG/DSC was used to evaluate the distribution of ceramics within the polymer matrix, and FTIR-ATR was used to confirm the molecular structure of composites. SEM/EDS analysis of the scaffolds revealed cavities and irregularities in the surface, and that cHAP was indistinctly exposed on the composite surface, computed tomography (CT) was used to estimate the density and homogeneity of the scaffolds, and the cHAP distribution within the scaffolds was evaluated by conventional radiography. The hydrophilicity of the multi-composite scaffolds was investigated using an aqueous solution of methylene blue dye which showed that the acrylate(75%)–gelatin(25%)–cHAP composite had the highest hydrophilicity. The results suggest that acrylate–gelatin–cHAP scaffolds have a potential for bone-tissue engineering. |
| Published |
London : The Royal Society of Chemistry |
| Type |
Journal article |
| Language |
English |
| Publication date |
2020 |
| CC license |
|
