| Title |
Anti-Yo antikūnų sukelta paraneoplastinė smegenėlių degeneracija. Atvejų pristatymas ir literatūros apžvalga |
| Translation of Title |
Paraneoplastic anti-Yo antibody mediated subacute cerebellar degeneration. Case series and literature review. |
| Authors |
Vaišvilas, Mantas ; Mameniškienė, Rūta ; Barkauskienė, A |
| DOI |
10.29014/ns.2020.08 |
| Full Text |
|
| Is Part of |
Neurologijos seminarai.. Vilnius : Rotas. 2020, t. 24, Nr. 1, p. 61-67.. ISSN 1392-3064. eISSN 2424-5917 |
| Keywords [eng] |
autoimmune encephalitis ; paraneoplastic neurologic syndrome ; antineuronal antibodies ; paraneoplastic cerebellar degeneration |
| Abstract [eng] |
Paraneoplastic neurologic syndromes are a subgroup of diseases due to indirect cytotoxic effects of the immune system on specific brain structures rather than the mass effect itself. Paraneoplastic anti-Yo antibody mediated subacute cerebellar degeneration is characterised by an insidious onset, a characteristic neurologic syndrome of cerebellar dysfunction, normal or near/normal brain imaging on MRI, and gynaecologic malignancies identified by thorough investigation in middle aged post-menopausal women. Despite various aggressive treatments available, the prognosis is often considered poor. We present two cases with classical findings consistent with paraneoplastic subacute cerebellar degeneration and give literature review. |
| Published |
Vilnius : Rotas |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2020 |
| CC license |
|
