Title Ūminio išeminio insulto gydymo intravenine trombolize baigties prognozavimas /
Translation of Title Predicting outcome of intravenous thrombolysis for acute ischenic stroke .
Authors Vilionskis, Aleksandras
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Pages 135
Keywords [eng] Ischemic stroke ; intravenous thrombolysis ; outcome ; prognosis ; prognostic model
Abstract [eng] The integrated analysis of safety and efficacy of intravenous thrombolysis for acute ischemic stroke patients in Lithuania the first time is presented in this doctoral dissertation. The acceptance of current prognostic models of outcome of ischemic stroke after intravenous thrombolysis for our community is investigated as well. The original prognostic model for our community according to established prognostic factors is done and proposed. 206 patients with acute ischemic stroke and treated with intravenous thrombolysis in Republican Vilnius University hospital and Vilnius University hospital Santariskiu Clinics 2010 – 2013 y. were included in this study. The relation of baseline demographical, clinical and imaging data and the relation with early and late outcome of stroke is analyzed. The results of treatment (efficacy and safety profile) of all patients are presented. The additional analysis for different subgroup analysis is done as well. The independent predictors of good outcome and significant early neurological improvement are identified. The unclear questions, that needs further studies is discussed in this doctoral dissertation. The next steps of scientific research in acute ischemic stroke field are proposed as well. The four practical recommendations are proposed. The results of this study could be helpful for all doctors, who is interesting in treatment of acute stroke patients. .
Dissertation Institution Vilniaus universitetas.
Type Doctoral thesis
Language Lithuanian
Publication date 2015