Title Association between vitamin D and bone mineral density in post-menopausal women with metabolic syndrome /
Translation of Title Vitamino D ir kaulų mineralų tankio ryšys moterims po menopauzės, sergančioms metaboliniu sindromu.
Authors Dadonienė, Jolanta ; Čypienė, Alma ; Rinkūnienė, Egidija ; Badarienė, Jolita ; Burca, Jelizaveta ; Sakaitė, Ieva ; Kalinauskaitė, Goda ; Kumpauskaitė, Vaiva ; Laucevičius, Aleksandras
DOI 10.6001/actamedica.v22i1.3074
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Is Part of Acta medica Lituanica.. Vilnius : Lietuvos mokslų akademijos leidykla. 2015, Vol. 22, no. 1, p. 7-14.. ISSN 1392-0138. eISSN 2029-4174
Keywords [eng] vitamin D ; bone mineral density ; metabolic syndrome
Abstract [eng] Background. The aim of this study was to identify the relation between vitamin D level and mineral bone density in post-menopausal women with metabolic syndrome. Materials and methods. This study included 100 post-menopausal women at age between 50 and 65 with metabolic syndrome. All participants underwent anthropometric measurements. Laboratory tests were performed to determine lipid profile, serum glucose, creatinine, C-reactive protein, vitamin D (25(OH) D), ionized calcium concentration and urine albumin / creatinine ratio. Bone mineral density of the lumbar spine (L1–L4) and total hip was measured by dual-energy X-ray absorptiometry. Results. According to the vitamin D concentration level in the blood all women were divided into four groups: the average failure was observed in 57%, mild failure in 33%, severe failure in 5%; and only 5% of women had normal vitamin levels. The mean 25(OH) D level was 47.40 ± 16.91 nmol/l. According to bone densitometry we found that 77% of all participants had normal bone mineral density, 22% had osteopenia and 5% were diagnosed with osteoporosis. No correlation was found between bone mineral density and 25(OH) D levels. We found a weak positive correlation between high density lipoprotein cholesterol and 25(OH) D (r = 0.3, p < 0.05) but no significant difference between 25(OH) D and other lipoproteins, calcium ions, glucose, C-reactive protein and urine albumin / creatinine ratio. Conclusions. Hypovitaminosis D is very common among post-menopausal women with metabolic syndrome. No relation was found between the 25(OH) D level and the bone mineral density.
Published Vilnius : Lietuvos mokslų akademijos leidykla
Type Journal article
Language English
Publication date 2015
CC license CC license description