Title Brain stimulation in eating disorders: state of the art and future perspectives /
Authors Duriez, Philibert ; Bou Khalil, Rami ; Chamoun, Yara ; Maatoug, Redwan ; Strumila, Robertas ; Seneque, Maude ; Gorwood, Philip ; Courtet, Philippe ; Guillaume, Sébastien
DOI 10.3390/jcm9082358
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Is Part of Journal of clinical medicine.. Basel : MDPI. 2020, vol. 9, iss. 8, art. no. 2358, p. [1-25].. ISSN 2077-0383
Keywords [eng] anorexia ; binge eating disorders ; bulimia ; deep brain stimulation ; rTMS ; treatment
Abstract [eng] The management of eating disorders (EDs) is still difficult and few treatments are effective. Recently, several studies have described the important contribution of non-invasive brain stimulation (repetitive transcranial magnetic stimulation, transcranial direct current stimulation, and electroconvulsive therapy) and invasive brain stimulation (deep brain stimulation and vagal nerve stimulation) for ED management. This review summarizes the available evidence supporting the use of brain stimulation in ED. All published studies on brain stimulation in ED as well as ongoing trials registered at clinicaltrials.gov were examined. Articles on neuromodulation research and perspective articles were also included. This analysis indicates that brain stimulation in EDs is still in its infancy. Literature data consist mainly of case reports, cases series, open studies, and only a few randomized controlled trials. Consequently, the evidence supporting the use of brain stimulation in EDs remains weak. Finally, this review discusses future directions in this research domain (e.g., sites of modulation, how to enhance neuromodulation efficacy, personalized protocols).
Published Basel : MDPI
Type Journal article
Language English
Publication date 2020
CC license CC license description