Title Malignant transformation of oral lichen planus in labial location in a 23-year-old woman - Case report
Authors Zawadzka, Barbara ; Pūrienė, Alina ; Rimkevičius, Arūnas
DOI 10.17219/dmp/60130
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Is Part of Dental and medical problems.. Wrocław : Wroclaw Medical University. 2015, vol. 52, no. 4, p. 512-515.. ISSN 1644-387X
Keywords [eng] dysplasia ; lichen planus ; lip ; malignant transformation ; young age
Abstract [eng] Lichen planus (LP) having a potential for malignant transformation is a rare mucocutaneous disease most frequently observed in middle-aged women than in men. LP is uncommon in young patients and the involvement of a labial site and desquamative gingivitis are also rare. LP mainly affects oral mucosa, and skin involvement is rare. Mucosal lesions are usually multiple and have a bilateral, symmetrical manifestation. Mucosal lesions frequently appear on the tongue, gingiva, and mucobuccal fold. Nearly half of the patients has multiple sites of involvement. Oral biopsy with a histopathological evaluation is necessary to validate the clinical diagnosis of LP. Malignant transformation is uncommon for young patients with a short history of LP and without the presence of other co-morbidities. The aim of the present report was to present a 23-year-old patient with an LP lesion which developed into a squamous cell carcinoma on a facial labial site. Different subject-related pathological, diagnostic and treatment aspects are discussed.
Published Wrocław : Wroclaw Medical University
Type Journal article
Language English
Publication date 2015
CC license CC license description