Title The Mutographs biorepository: A unique genomic resource to study cancer around the world /
Authors Perdomo, Sandra ; Abedi-Ardekani, Behnoush ; de Carvalho, Ana Carolina ; Ferreiro-Iglesias, Aida ; Gaborieau, Valérie ; Cattiaux, Thomas ; Renard, Hélène ; Chopard, Priscilia ; Carreira, Christine ; Spanu, Andreea ; Nikmanesh, Arash ; Cardoso Penha, Ricardo Cortez ; Antwi, Samuel O ; Ashton-Prolla, Patricia ; Canova, Cristina ; Chitapanarux, Taned ; Cox, Riley ; Curado, Maria Paula ; de Oliveira, José Carlos ; Dzamalala, Charles ; Fabianova, Elenora ; Ferri, Lorenzo ; Fitzgerald, Rebecca ; Foretova, Lenka ; Gallinger, Steven ; Goldstein, Alisa M ; Holcatova, Ivana ; Huertas, Antonio ; Janout, Vladimir ; Jarmalaitė, Sonata ; Kaneva, Radka ; Kowalski, Luiz Paulo ; Kulis, Tomislav ; Lagiou, Pagona ; Lissowska, Jolanta ; Malekzadeh, Reza ; Mates, Dana ; McCorrmack, Valerie ; Menya, Diana ; Mhatre, Sharayu ; Mmbaga, Blandina Theophil ; de Moricz, André ; Nyirády, Péter ; Ognjanovic, Miodrag ; Papadopoulou, Kyriaki ; Polesel, Jerry ; Purdue, Mark P ; Rascu, Stefan ; Rebolho Batista, Lidia Maria ; Reis, Rui Manuel ; Ribeiro Pinto, Luis Felipe ; Rodríguez-Urrego, Paula A ; Sangkhathat, Surasak ; Sangrajrang, Suleeporn ; Shibata, Tatsuhiro ; Stakhovsky, Eduard ; Świątkowska, Beata ; Vaccaro, Carlos ; Vasconcelos de Podesta, Jose Roberto ; Vasudev, Naveen S ; Vilensky, Marta ; Yeung, Jonathan ; Zaridze, David ; Zendehdel, Kazem ; Scelo, Ghislaine ; Chanudet, Estelle ; Wang, Jingwei ; Fitzgerald, Stephen ; Latimer, Calli ; Moody, Sarah ; Humphreys, Laura ; Alexandrov, Ludmil B ; Stratton, Michael R ; Brennan, Paul
DOI 10.1016/j.xgen.2024.100500
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Is Part of Cell genomics.. Cell Press. 2024, vol. 4, iss. 3, art. no. 100500, p. [1-11].. ISSN 2666-979X. eISSN 2666-979X
Abstract [eng] Large-scale biorepositories and databases are essential to generate equitable, effective, and sustainable advances in cancer prevention, early detection, cancer therapy, cancer care, and surveillance. The Mutographs project has created a large genomic dataset and biorepository of over 7,800 cancer cases from 30 countries across five continents with extensive demographic, lifestyle, environmental, and clinical information. Whole-genome sequencing is being finalized for over 4,000 cases, with the primary goal of understanding the causes of cancer at eight anatomic sites. Genomic, exposure, and clinical data will be publicly available through the International Cancer Genome Consortium Accelerating Research in Genomic Oncology platform. The Mutographs sample and metadata biorepository constitutes a legacy resource for new projects and collaborations aiming to increase our current research efforts in cancer genomic epidemiology globally.
Published Cell Press
Type Journal article
Language English
Publication date 2024
CC license CC license description